Anika Vear (Class of 2014)

My research is looking at the development and testing of new drugs for treating cardiac fibrosis. The build-up of scar tissue (i.e., fibrosis) in the heart is one of the key contributing factors in the development of cardiovascular disease and the progression to end-stage heart failure. Our lab has developed new compounds which are able to reverse cardiac fibrosis in mice by breaking down this scar tissue and improving the contractile function of the heart.

The aim of my research is to better understand how these drugs work at a cellular level. I am developing new techniques to visualise and track the drugs binding to its target on different cell types involved in fibrosis such as the contractile cells of the heart, fibroblasts, and immune cells like macrophages. Ultimately, my research will help to bring us one step closer to progressing into clinical trials, in the hope that one day we can reverse established fibrosis in patients and prevent their progression to end-stage heart failure.

About the Foundation Scholarship

The Mentone Grammar Foundation provides the opportunity for Mentonians to apply for a grant of up to $15,000 to assist with the pursuit of Doctoral studies. The Mentonians Association and broader Mentone Grammar Community proudly supports our students to continue to ‘dream big’, long after they leave school.